For regenerative medicine,
there are many challenges .
- It is hard to
obtain enough
number of cells. - It is hard to
assure
medical-grade
safety - It is hard to
maintain the
potential of
therapeutic cell
Kuraray’s microcarriers
can solve these problems!
3 reasons you choose
Kuraray’s microcarrier
1. Good cell proliferation rate
Our microcarrier can be applied
to cultivate therapeutic cells
like MSCs.
Human cells cultured on each
microcarriers for 7days.
The proliferation rate vs.
initial cell number was estimated.
Our microcarriers have higher cell proliferation capability than competitors.
We have demonstrated 100l scale culture.
2. Quality management in accordance with medical standards
Our microcarrier made from Kuraray’s PVA(※). We conduct strict quality management. And there is no risk of contamination due to the material features.
(※)Polyvinyl Alcohol
Our microcarriers are not broken by collision during agitation. Because PVA material has excellent elasticity.
※This animation shows compression test of our microcarrier (Red arrow)
| Safety test | Result |
|---|---|
| Endotoxin | ＜0.01EU/cm2 |
| Sterilization | SAL 10-6 (by gamma irradiation) |
| Cytotoxicity Genotoxicity Systemic acute toxicity Implantation test |
Negative (Tested in accordance with ISO 10993.) |
| Leachable Extractable |
Tested in accordance with BPOG guideline. |
For more information, please contact us.
3. Ease of handling
The use of Kuraray’s micocarriers is easy. It is “Ready to use”. No need for sterilization and cleaning before using. It swells quickly in PBS or medium.
Swollen particle is highly transparency. Therefore, cells can be easily observed with a phase contrast microscope.
Particles swell quickly in medium or PBS.
Cells can be easily observed with a phase contrast microscope.
Product list
・PVA Microcarriers CL
The surface of particles is coated with collagen and clinically usable collagen is adopted. Endotoxin and virus in the collagen have been reduced or inactivated.
To realize regenerative
medicine,
Kuraray’s microcarrier
is best choice!
Customer service, sample request,
technical questions.
